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Organometallic compounds contain direct bonds between carbon atoms and metal atoms/ions and play roles as homogeneous catalysts and stoichiometric reagents in reactions; available in various chemical compositions, quantities, purities, and reagent grades.
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Benzylboronic acid pinacol ester is a biochemical reagent suitable for life science research. With a purity of 97.0%, it appears as a colorless to off-white solid-liquid mixture and is soluble in DMSO at 100 mg/mL. This compound is utilized in Pd(0)-mediated [11C] carbonylation reactions.
Biochemical reagent for life science research.
Utilized in Pd(0)-mediated carbonylation reactions.
Soluble in DMSO at 100 mg/mL.
Pure form storage: -20°C for 3 years.
In solvent storage: -80°C for 6 months; -20°C for 1 month.
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Sitafloxacin hydrate is an orally active fluoroquinolone antibiotic with in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria, as well as atypical pathogens. It is used in the study of respiratory tract infections and urinary tract infections. This product is for research use only.
Has in vitro activity against a wide range of Gram-positive and -negative bacteria, including anaerobic bacteria and atypical pathogens.
Effective in the study of respiratory tract infections.
Useful in the study of urinary tract infections.
Shows good activity against Mycobacterium avium in mice, effectively eliminating bacteria in the spleen and lungs.
Exhibits strong activity against mycobacteria in macrophages.
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Acetoacetic acid sodium is an oxidative stress inducer impacting the antioxidant enzyme system and lipoprotein metabolism. It can be utilized in metabolic disease studies, as it induces oxidative stress and inhibits very low-density lipoprotein (VLDL) assembly in hepatocytes.
Decreases mRNA expression and activity of antioxidant enzymes (SOD, CAT, GSH-Px).
Increases malondialdehyde (MDA) content.
Downregulates apolipoprotein ApoB100, ApoE, and low density lipoprotein receptor (LDLR).
Promotes triglyceride (TG) accumulation in hepatocytes.
Requires fresh preparation due to instability in solutions.
Recommended storage at -80°C under nitrogen.
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If you are unable to find the chemical you are looking for, make sure you are logged into your fishersci.com account and click on the following link: eMolecules Building Block Tool<|a>
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N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Used in the synthesis of PROTACs
Connects two ligands in PROTACs
Facilitates protein degradation via ubiquitin-proteasome system
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N-Boc-C1-PEG3-C3-NH2 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. They exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
PEG-based PROTAC linker
Can be used in the synthesis of PROTACs
Exploits the intracellular ubiquitin-proteasome system
Selectively degrades target proteins
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